Mutations of FII and FV factors of Coagulation and MTHFR

Atherosclerosis and venous thrombosis are the two major manifestations of CVD. Both are caused by complex interactions of environmental and genetic parameters. An unhealthy lifestyle in combination with certain genetic variants can contribute to atherosclerosis. Relevant genes include those involved in endothelial dysfunction, hyperlipidemia, hypertension, and inflammation. Similarly, a combination of adverse influences (female hormone intake, immobilization, surgery or cancer) and variations in genes responsible for the coagulation system can lead to thrombosis. CVD are common, but in many cases they can be avoided. Testing for the genetic variations can greatly contribute to lowering the individual CVD risk. The best way for avoidance is a lifestyle that is in accordance with an individual's genetic predisposition. 

Specimen Requirements - 2 ml of peripheral blood collected in an EDTA (lavender top) vacutainer tube.

Transport - the specimen should be refrigerated (for 1or 2 days) and shipped at room temperature. 

Reporting time - 10-15 days 

(DNA test for detection of genetic variants associated with CVD: FV G1601A (Leiden), FV H1299R (R2), Prothrombin G20210A, MTHFR C677T, MTHFR A1298C, Factor XII V34L, PAI-1 4G/5G, EPCR A4600G, EPCR G4678C). 

For further information please contact:
Tel.: (+374 10) 544367
Fax: (+374 10) 544366
E-mail: infocmg@genetics.sci.am

Цена: 30 000 AMD