Warfarin (Coumarin) anticoagulant therapy optimization -VKORC1 and CYP2C9 | |
Stroke, myocardial infarction and venous thromboembolism are commonly treated and prevented by oral anticoagulants. Vitamin K antagonists (coumarins) are highly effective for that purpose. However, their narrow therapeutic range in combination with a wide variability in dose response poses a considerable risk to patients. Consequences of an inappropriate coumarin dose include life-threatening bleeding (overdose) or lack of therapeutic effect (insufficient dose). Hence, an individualized anticoagulation treatment is of paramount importance for the safety and health of patients. |
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Цена: 30 000 AMD |