|Free Beta-Subunit of Human Chorionic Gonadotropin (Free –BHCG)|
Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone normally produced by placenta during pregnancy. hCG molecules consist of two non-covalently linked polypeptide subunits, the alpha and beta chain subunits. In the first trimester of pregnancy, screening together with ultrasound markers (the nuchal translucency, NT), maternal serum β-hCG and PAPP-A can identify up to 97% of fetuses with trisomy 21 and other major chromosomal abnormalities.
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