AFP is a glycoprotein made in the liver of an unborn baby (fetus). The amount of AFP in the blood of a pregnant woman can help to identify whether the baby may have such conditions as spina bifida and anencephaly. An AFP test is as part of the screening test to find other chromosomal changes, such as Down syndrome (trisomy 21) or Edward’s syndrome (trisomy 18). AFP is also used as tumor marker to help detect and diagnose cancers of the liver, testes1 and ovaries.
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